Treballs de recerca
- Unitat VIH - SIDA  -
 

TNF-alfa i immunopatogenesi
Recursos assistencials
Terapia antiretroviral
Manifestacions clíniques
 

Responsable de la informació: 
Dr. Manel Cervantes - mcervantes@tauli.cat
Responsable de la Unitat VIH-SIDA

Darrera actualització 06/06/08


 

 

 

 

 

TNF-alfa i immunopatogenesi  

TNF-alfa en los pacientes infectados por el VIH. Valor pronóstico.
Investigador principal: M. Sala
Beca FIS
Apoptosis en pacientes infectados por VIH
Investigador principal: M. J. Amengual
Beca Fundació Parc Taulí
 
1994
TNF production in HIV- infected patients. Utility as surrogate marker and relationship with opportunistic infections.
Sala M, Monteagudo M, Amengual MJ, Sasal M, Cervantes M, Segura F
X International Conference on AIDS. poster PA-0267 , Yokohama, 7-12 agost 1994
 
1995
Tumor Necrosis Factor in HIV infected patients. Correlation with opportunistic diseases.
Sala M, CervantesM, Sasal M, FontB, SerrateG, Amengual MJ, Segura F
I International Symposium Cytokines and HIV, poster, Reims 1995
 
Apoptosis of lymphocytic cells in HIV infected patients
Amengual MJ, Sala M, Sasal M, Cervantes M, Segura F
I International Symposium Cytokines and HIV, poster, Reims 1995
 
Implicación de TNF-alfa y CD 95 / Fas en la apoptosis de linfocitos de pacientes infectados por el VIH.
Amengual MJ, Sala M, Ustrell R, Monteagudo M, Cervantes M, Oristrell J, Sasal M, Segura F
Jornada de Investigación sobre la patogenia del Sida.
Institut Français de Madrid, poster, octubre de 1995
 
1998
Predicting clinical progression and death in a cohort of HIV- infected patients. A comparative analysis of HIV-RNA and TNF-alfa.
SalaM, CervantesM, RodriguezM, AmengualMJ, RueM, SasalM, Segura F
XII International Conference on AIDS . Poster 42188, Geneve, 28 jun-3 jul 1998
 
1999
Progression and mortality in a cohort of HIV-infected patients in Pre-HAART era: a comparison between viral load, CD4 and TNF-alpha levels.
Sala M, Cervantes M, Amengual MJ, SasalM, Font B, Serrate G, Segura F
39th ICAAC; September 26-29, 1999; San Francisco, Calif. Abstract 126.
comentaris de Graeme Moyle, a Medscape's ICAAC summaries: Natural History and Opportunistic Infections in HIV Disease
 

 

Recursos assistencials 

1998

HAART in clinical practice: the improvement in parameters of hospital activity confirms effectiveness of new therapies.
Cervantes M, Sala M, Sasal M, Font B, Serrate G, Vidal G, Segura F
XII International Conference on AIDS . Poster 42437.Ginebra, 28 jun-3 jul 1998
 

 

Teràpia antiretroviral 

1996
Plasma Viral Load and CD4 changes in naive patients at 3 months after initiation of combined therapy with zidovudine and zalcitabine.
Ibañez A, Ruiz L, Puig T, Gutierrez C, Sanzhez I, Clotet B and the Group for the Study of Viral Load in patients undergoing combination therapy.
XI International Conference on Aids. poster, Vancouver, 1996
 
1997
Immunological and virological activity of zalcitabine and zidovudine in combination in HIV-positive people with CD4 between 200-500 cells/mm3
IbáñezA, PeraireJ, ArnóA, GutiérrezC, CervantesM, ColomerJ, VillalongaC, CamafortM, RuizL, BalaguerM, VidalF, Richart C, Clotet B
Antiviral therapy 1997; 2: 105-12
 
1998
Hyperglycemia associated with protease inhibitor therapy
Sala M, Peña R, Cervantes M, Font B, Serrate G, Segura F
XII International Conference on AIDS . Poster 12387 Geneve, 28 jun-3 jul 1998
 
1999
Nelfinavir / Saquinavir drug levels in two different dosage schedules: a pilot study
Dalmau D, Gomez L, Martinez-Lacasa X, Cervantes M, Knobel H, Domingo P, Garau J
European Conference on Clinical Aspects of Aids. Berlin, 1999
 
Efficacy of salvage therapy containing nelfinavir and saquinavir after failure of single protease inhibitor containing regimens
Domingo P, Cervantes M, Gomez L, Rodriguez Carballeira M, Pedrol E, Knobel H, Martinez-Lacasa X, Guardiola J, Sala M, Solé R, Dalmau D
Seventh European Conference on Clinical Aspects and Treatment of HIV Infection, poster, Lisboa, octubre 1999
 
Liver function tests before and after HAART: longitudinal study of a cohort of 119 patients through six years (1993-99)
Cervantes M, Navarro M, Sala, Font B, Serrate G, Segura F
Seventh European Conference on Clinical Aspects and Treatment of HIV Infection, póster, Lisboa, octubre 1999
 
Prevalence of AZT and 3TC resistance related mutations in the absence of active AZT or 3TC use in a large, multi-centered, comparative trial of Genotyping and Standard of Care - The Havanna Trial
Ruiz L, Tural C, Holtzer C, Boulme R, Martinez-Picado X, Vilaro J, Cervantes M, Ferrer E, Guelar A, Iribarren JA, Massaveu A, Llibre JM, Peraire J, Clotet B and the Havanna Study Group.
4th International Workshop on Drug Resistance and Treatment Strategies
Sitges, Barcelona. June 12-16, 2000
 

An open randomized study comparing d4T + ddI and nevirapine (Qd) vs d4T + ddI and nevirapine (Bid) in antiretroviral naive chronic HIV-1 infected patients in very early stages: Spanish scan study. Final results.

F Garcia, H Knobel, MA Sambeat, J Arrizabalaga, M. Aranda, J Romeu, D Dalmau, F Segura, Jose Luis G-S, E Ferrer, Anna C, T Gallart, T Pumarola, JM Miró, JM Gatell

XIII World Aids Conference, Durban, july 2000

 

Efficacy of salvage therapy containing Nelfinavir / Saquinavir combination and their correlation with genotypic resistance pattern.

D. Dalmau, M. Rodriguez Carballeira, L. Gomez, E. Pedrol, R. Sole, H. Knobel, P. Domingo, M. Cervantes, M. Sala, J. Guardiola, X. Martinez Lacasa

XIII World Aids Conference, Durban, july 2000

 

Comparison of twice-daily stavudine plus once- or twice-daily didanosine and nevirapine in early stages of HIV infection: the Scan Study

Felipe Garcia, Hernando Knobel, Maria Antonia Sambeat, Julio Arrizabalaga, Miquel Aranda, Joan Romeu, David Dalmau, Ferran Segura, Juan Luis Gomez-Sirvent, Elena Ferrer, Anna Cruceta, Teresa Gallart, Tomas Pumarola, Jose M Miro, Jose M Gatell and The Spanish Scan Study Group

AIDS, 2000;14:2485-94

 

Comparison of Immunologic Restoration and Virologic Response in Plasma, Tonsillar Tissue, and Cerebrospinal Fluid in HIV-1–Infected Patients Treated With Double Versus Triple Antiretroviral Therapy in Very Early Stages: The Spanish Earth-2 Study

Felipe García; María M. Alonso; Joan Romeu; Hernando Knobel; Julio Arrizabalaga; Elena Ferrer; David Dalmau; Isabel Ruiz; Francesc Vidal; Adela Frances; Ferran Segura; Juan L. Gomez -Sirvent; Anna Cruceta; Bonaventura Clotet; Tomás Pumarola; Teresa Gallart; William A. O'Brien; José M. Miró; José M. Gatell; Spanish Earth-2 Study

JAIDS, 2000;25:26-35

 

Manifestacions clíniques 

1992
Rhodococcus equipulmonary infection in an HIV infected patient
Sasal M, Roig J, Cervantes M, Ormaza J, Matas L, Segura F
VIII International Conference on Aids, Amsterdam, poster, 19.24 juliol 1992
 
Good response to antibiotic treatment of lung infection due to Rhodococcus equi in a patient infected with HIV
Sasal M, Roig J, Cervantes M, Matas L, Segura F
Clin Infect Dis 1992; 15: 747-8
 
1993
Gastric mucormycosis in a patient with AIDS
Brullet E, Andreu X, Elias J, Roig J, Cervantes M
Gastrointestinal Endoscopy 1993; 39:106-7
 
Esophageal infection by cryptococcus and CMV with mediastinal fistula
Sasal M, Serrate G, Chapinal O, Brullet E, Cervantes M, Segura F
IX International Conference on Aids. Poster B19-1852, Berlin 6-11 juny 1993
 
1994
Gastric tuberculosis as first manifestation of AIDS. Presentation of a case with antral fistula.
Sasal M, Sala M, Serrate, Font B, Cervantes M, Segura F
X International Conference on AIDS. Poster PB-0676, Yokohama, 7-12 agost 1994
 
1995
Evaluation of a PCR commercial kit for rapid diagnosis of tuberculosis in HIV infected patients.
MariscalD, SasalM, RenauJ, CervantesM, FontanalsD, Segur F, Torra M
3d Scientific Meeting European Society of Chemotherapy Infectious Diseases, Institut Pasteur, Paris, 18-20 maig 1995
 
1996
Quistes linfoepiteliales de parótida en pacientes con infección por VIH. Presentación de 4 casos.
Font J, Sala M, Sasal M, Donoso L, Segura F, Cervantes M
XX Symposium Internacional de la Sociedad Española de Cirujanos de Cabeza y Cuello. Sabadell, 12-14 de desembre 1996 poster
 
1998
Aids in the elderly: a challenge to the internist
Cervantes M, Nogueras C, Sala M, Segura F, de Nadal J
Congreso Mundial de la International Society of Internal Medicine Lima, noviembre de 1998 poster
 
Hyperglycemia associated with protease inhibitor therapy
Sala M, Peña R, Cervantes M, Font B, Serrate G, Segura F
XII International Conference on AIDS . Poster 12387 Geneve, 28 jun-3 jul 1998
 
1999

Liver function tests before and after HAART: longitudinal study of a cohort of 119 patients through six years (1993-99)

Cervantes M, Navarro M, Sala, Font B, Serrate G, Segura F
Seventh European Conference on Clinical Aspects and Treatment of HIV Infection, poster, Lisboa, octubre 1999
 

2000

Osteonecrosis in HIV+ patients: Five more cases of another metabolic disorder associated with HAART?

MCervantes , CNogueras, MSala, BFont, GSerrate, FSegura, MLarrosa

XIII World Aids Conference, Durban, july 2000

 
Neoplasia of plasma cells with atypical presentation and infection by the Human Immunodeficiency Virus. A presentation of two cases
Susana Herranz, Montserrat Sala, Manuel Cervantes, Mercè Sasal, Alfons Soler, Ferran Segura
American Journal of Hematology, 2000;65:239-42